منابع مشابه
Intestinal lipid handling: evidence and implication of insulin signaling abnormalities in human obese subjects.
OBJECTIVE Animal models have evidenced the role of intestinal triglyceride-rich lipoprotein overproduction in dyslipidemia. However, few studies have confronted this issue in humans and disclosed the intrinsic mechanisms. This work aimed to establish whether intestinal insulin resistance modifies lipid and lipoprotein homeostasis in the intestine of obese subjects. APPROACH AND RESULTS Duoden...
متن کاملIntestinal lipid absorption.
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has advanced considerably. Researchers have identified several new mechanisms by which lipids are taken up by enterocytes and packaged as chylomicrons for export into the lymphatic system or clarified the actions of mechanisms previously known to participate in these processes. Fatty acids are taken up by enterocy...
متن کاملThyroid hormones, mitochondrial bioenergetics and lipid handling.
PURPOSE OF REVIEW The article is principally intended to describe the recent evolutions in the field of research concerned with the metabolic actions of thyroid hormones and those of some of their metabolites or derivatives. Mitochondria, as a result of their functions, represent the principal objective of scientists investigating the mechanisms underlying the effects of thyroid hormones or the...
متن کاملIntestinal lipid absorption and transport.
The purpose of this review is to update the reader on our current knowledge of the digestion, uptake, and transport of dietary lipid. In particular, it discusses how intestinal lipid transporters may play a role in the uptake of lipids by the enterocytes, and how chylomicrons are formed in the enterocytes and packaged for export into the lymphatic system through exocytosis. The classification a...
متن کاملEffect of catechin on intestinal lipid metabolism.
On analysing the effect of catechin on intestinal lipid metabolism, an increase in the concentration of cholesterol in the duodenum and jejunum was observed along with an increase in the HMGCoA reductase activity. In the in vitro experiments also it was found that cholesterol and free fatty acid (FFA) levels were increased in these two regions. Binding of catechin with cholesterol in the lumen,...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2014
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.113.302993